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IFIT1: A dual sensor and effector molecule that detects non-2′-O methylated viral RNA and inhibits its translation
Our understanding of the antiviral actions of IFIT1, one of the most strongly induced interferon stimulated genes (ISGs), has advanced remarkably within the last few years. This review focuses on the recent cellular, biochemical, and structural discoveries that have provided new insight as to how IF...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Ltd.
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234691/ https://www.ncbi.nlm.nih.gov/pubmed/24909568 http://dx.doi.org/10.1016/j.cytogfr.2014.05.002 |