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Mechanistic stochastic model of histone modification pattern formation

BACKGROUND: The activity of a single gene is influenced by the composition of the chromatin in which it is embedded. Nucleosome turnover, conformational dynamics, and covalent histone modifications each induce changes in the structure of chromatin and its affinity for regulatory proteins. The dynami...

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Detalles Bibliográficos
Autores principales: Anink-Groenen, Lisette C M, Maarleveld, Timo R, Verschure, Pernette J, Bruggeman, Frank J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234852/
https://www.ncbi.nlm.nih.gov/pubmed/25408711
http://dx.doi.org/10.1186/1756-8935-7-30