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KAT6A, a Chromatin Modifier from the 8p11-p12 Amplicon is a Candidate Oncogene in Luminal Breast Cancer

The chromosome 8p11-p12 amplicon is present in 12% to 15% of breast cancers, resulting in an increase in copy number and expression of several chromatin modifiers in these tumors, including KAT6A. Previous analyses in SUM-52 breast cancer cells showed amplification and overexpression of KAT6A, and s...

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Detalles Bibliográficos
Autores principales: Turner-Ivey, Brittany, Guest, Stephen T., Irish, Jonathan C., Kappler, Christiana S., Garrett-Mayer, Elizabeth, Wilson, Robert C., Ethier, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234874/
https://www.ncbi.nlm.nih.gov/pubmed/25220592
http://dx.doi.org/10.1016/j.neo.2014.07.007