Cargando…
KAT6A, a Chromatin Modifier from the 8p11-p12 Amplicon is a Candidate Oncogene in Luminal Breast Cancer
The chromosome 8p11-p12 amplicon is present in 12% to 15% of breast cancers, resulting in an increase in copy number and expression of several chromatin modifiers in these tumors, including KAT6A. Previous analyses in SUM-52 breast cancer cells showed amplification and overexpression of KAT6A, and s...
Autores principales: | Turner-Ivey, Brittany, Guest, Stephen T., Irish, Jonathan C., Kappler, Christiana S., Garrett-Mayer, Elizabeth, Wilson, Robert C., Ethier, Stephen P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234874/ https://www.ncbi.nlm.nih.gov/pubmed/25220592 http://dx.doi.org/10.1016/j.neo.2014.07.007 |
Ejemplares similares
-
Oncogenic signaling in amphiregulin and EGFR‐expressing PTEN‐null human breast cancer
por: Kappler, Christiana S., et al.
Publicado: (2014) -
Amplification of WHSC1L1 regulates expression and estrogen‐independent activation of ERα in SUM‐44 breast cancer cells and is associated with ERα over‐expression in breast cancer
por: Irish, Jonathan C., et al.
Publicado: (2016) -
Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death
por: Guest, Stephen T., et al.
Publicado: (2016) -
Development and implementation of the SUM breast cancer cell line functional genomics knowledge base
por: Ethier, Stephen P., et al.
Publicado: (2020) -
ATM and KAT5 safeguard replicating chromatin against formaldehyde damage
por: Ortega-Atienza, Sara, et al.
Publicado: (2016)