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Citrulline uptake in rat cerebral cortex slices: Modulation by Thioacetamide -Induced hepatic failure

L-citrulline (Cit) is a co-product of NO synthesis and a direct L-arginine (Arg) precursor for de novo NO synthesis. Acute liver failure (ALF) is associated with increased nitric oxide (NO) and cyclic GMP (cGMP) synthesis in the brain, indirectly implicating a role for active transport of Cit. In th...

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Detalles Bibliográficos
Autores principales: Zielińska, Magdalena, Obara-Michlewska, Marta, Hilgier, Wojciech, Albrecht, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234898/
https://www.ncbi.nlm.nih.gov/pubmed/24385142
http://dx.doi.org/10.1007/s11011-013-9472-5