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Knockdown of Bcl-xL Enhances Growth-Inhibiting and Apoptosis-Inducing Effects of Resveratrol and Clofarabine in Malignant Mesothelioma H-2452 Cells

Mcl-1 and Bcl-xL, key anti-apoptotic proteins of the Bcl-2 family, have attracted attention as important molecules in the cell survival and drug resistance. In this study, we investigated whether inhibition of Bcl-xL influences cell growth and apoptosis against simultaneous treatment of resveratrol...

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Detalles Bibliográficos
Autores principales: Lee, Yoon-Jin, Hwang, In-Sung, Lee, Yong-Jin, Lee, Chang-Ho, Kim, Sung-Ho, Nam, Hae-Saeon, Choi, Young-Jin, Lee, Sang-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234912/
https://www.ncbi.nlm.nih.gov/pubmed/25408576
http://dx.doi.org/10.3346/jkms.2014.29.11.1464