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Gemcitabine as a molecular targeting agent that blocks the Akt cascade in platinum-resistant ovarian cancer
BACKGROUND: Gemcitabine (2′, 2′ –difluorodeoxycytidine) is one of many nonplatinum drugs that exhibit activity in recurrent, platinum-resistant ovarian cancer. However, the molecular mechanisms by which Gemcitabine treatment inhibits the proliferation of platinum-resistant ovarian cancer cells still...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234938/ https://www.ncbi.nlm.nih.gov/pubmed/24713296 http://dx.doi.org/10.1186/1757-2215-7-38 |