Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma

Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiological agent of primary effusion lymphoma (PEL), which represents a rapidly progressing malignancy arising in HIV-infected patients. Conventional chemotherapy for PEL treatment induces unwanted toxicity and is ineffective — PEL continues to...

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Detalles Bibliográficos
Autores principales: Dai, Lu, Cao, Yueyu, Chen, Yihan, Parsons, Chris, Qin, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234972/
https://www.ncbi.nlm.nih.gov/pubmed/24708874
http://dx.doi.org/10.1186/1756-8722-7-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234972/
https://www.ncbi.nlm.nih.gov/pubmed/24708874
http://dx.doi.org/10.1186/1756-8722-7-30

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