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Deregulation of the Replisome Factor MCMBP Prompts Oncogenesis in Colorectal Carcinomas through Chromosomal Instability()()

Genetic instability has emerged as an important hallmark of human neoplasia. Although most types of cancers exhibit genetic instability to some extent, in colorectal cancers genetic instability is a distinctive characteristic. Recent studies have shown that deregulation of genes involved in sister c...

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Detalles Bibliográficos
Autores principales: Quimbaya, Mauricio, Raspé, Eric, Denecker, Geertrui, De Craene, Bram, Roelandt, Ria, Declercq, Wim, Sagaert, Xavier, De Veylder, Lieven, Berx, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235010/
https://www.ncbi.nlm.nih.gov/pubmed/25246271
http://dx.doi.org/10.1016/j.neo.2014.07.011