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Establishing Restricted Expression of Caveolin-1 in HIV Infected Cells and Inhibition of Virus Replication

BACKGROUND: Caveolin-1 (Cav-1) is the major protein of the caveolae and plays a role in multiple cellular functions and implicated to have anti-HIV activity. Regulated expression of Cav-1 is important for safe and effective use in order to exploit Cav-1 for HIV therapeutic applications. METHODS: A s...

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Detalles Bibliográficos
Autores principales: Lo, Yung-Tsun, Nadeau, Peter E, Lin, Shanshan, Mergia, Ayalew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235073/
https://www.ncbi.nlm.nih.gov/pubmed/25408776
http://dx.doi.org/10.2174/1874285801408010114