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Upregulation of CD11A on Hematopoietic Stem Cells Denotes the Loss of Long-Term Reconstitution Potential

Small numbers of hematopoietic stem cells (HSCs) generate large numbers of mature effector cells through the successive amplification of transiently proliferating progenitor cells. HSCs and their downstream progenitors have been extensively characterized based on their cell-surface phenotype and fun...

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Detalles Bibliográficos
Autores principales: Fathman, John W., Fernhoff, Nathaniel B., Seita, Jun, Chao, Connie, Scarfone, Vanessa M., Weissman, Irving L., Inlay, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235136/
https://www.ncbi.nlm.nih.gov/pubmed/25418718
http://dx.doi.org/10.1016/j.stemcr.2014.09.007