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Single-Cell Analysis of Proxy Reporter Allele-Marked Epithelial Cells Establishes Intestinal Stem Cell Hierarchy

The recent development of targeted murine reporter alleles as proxies for intestinal stem cell activity has led to significant advances in our understanding of somatic stem cell hierarchies and dynamics. Analysis of these reporters has led to a model in which an indispensable reserve stem cell at th...

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Detalles Bibliográficos
Autores principales: Li, Ning, Yousefi, Maryam, Nakauka-Ddamba, Angela, Jain, Rajan, Tobias, John, Epstein, Jonathan A., Jensen, Shane T., Lengner, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235148/
https://www.ncbi.nlm.nih.gov/pubmed/25418730
http://dx.doi.org/10.1016/j.stemcr.2014.09.011