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let-7 miRNAs Can Act through Notch to Regulate Human Gliogenesis
It is clear that neural differentiation from human pluripotent stem cells generates cells that are developmentally immature. Here, we show that the let-7 plays a functional role in the developmental decision making of human neural progenitors, controlling whether these cells make neurons or glia. Th...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235151/ https://www.ncbi.nlm.nih.gov/pubmed/25316189 http://dx.doi.org/10.1016/j.stemcr.2014.08.015 |