Defining the Role of Oxygen Tension in Human Neural Progenitor Fate

Hypoxia augments human embryonic stem cell (hESC) self-renewal via hypoxia-inducible factor 2α-activated OCT4 transcription. Hypoxia also increases the efficiency of reprogramming differentiated cells to a pluripotent-like state. Combined, these findings suggest that low O(2) tension would impair th...

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Detalles Bibliográficos
Autores principales: Xie, Yuan, Zhang, Jin, Lin, Ying, Gaeta, Xavier, Meng, Xiangzhi, Wisidagama, Dona R.R., Cinkornpumin, Jessica, Koehler, Carla M., Malone, Cindy S., Teitell, Michael A., Lowry, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235163/
https://www.ncbi.nlm.nih.gov/pubmed/25418722
http://dx.doi.org/10.1016/j.stemcr.2014.09.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235163/
https://www.ncbi.nlm.nih.gov/pubmed/25418722
http://dx.doi.org/10.1016/j.stemcr.2014.09.021

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