Neuroprotective maraviroc monotherapy in simian immunodeficiency virus-infected macaques: reduced replicating and latent SIV in the brain

OBJECTIVE: HIV-associated neurocognitive deficits remain a challenge despite suppressive combined antiretroviral therapy. Given the association between HIV-induced central nervous system (CNS) disease and replication of HIV in immune-activated macrophages, CCR5 antagonists may attenuate CNS disease...

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Detalles Bibliográficos
Autores principales: Kelly, Kathleen M., Beck, Sarah E., Pate, Kelly A. Metcalf, Queen, Suzanne E., Dorsey, Jamie L., Adams, Robert J., Avery, Lindsay B., Hubbard, Walter, Tarwater, Patrick M., Mankowski, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2013
Materias:
Fast Track
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235167/
https://www.ncbi.nlm.nih.gov/pubmed/24051706
http://dx.doi.org/10.1097/QAD.0000000000000074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235167/
https://www.ncbi.nlm.nih.gov/pubmed/24051706
http://dx.doi.org/10.1097/QAD.0000000000000074

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