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Neuroprotective maraviroc monotherapy in simian immunodeficiency virus-infected macaques: reduced replicating and latent SIV in the brain
OBJECTIVE: HIV-associated neurocognitive deficits remain a challenge despite suppressive combined antiretroviral therapy. Given the association between HIV-induced central nervous system (CNS) disease and replication of HIV in immune-activated macrophages, CCR5 antagonists may attenuate CNS disease...
Autores principales: | Kelly, Kathleen M., Beck, Sarah E., Pate, Kelly A. Metcalf, Queen, Suzanne E., Dorsey, Jamie L., Adams, Robert J., Avery, Lindsay B., Hubbard, Walter, Tarwater, Patrick M., Mankowski, Joseph L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235167/ https://www.ncbi.nlm.nih.gov/pubmed/24051706 http://dx.doi.org/10.1097/QAD.0000000000000074 |
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