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Age-associated decrease in global DNA methylation in patients with major depression

BACKGROUND: Evidence has supported a role of DNA methylation in the pathophysiology of mood disorders. The purpose of the current study is to examine 5-methylcytosine (5-mc) and 5-hydroxymethylcytosine (5-hmc) levels in patients with major depressive disorder (MDD) at different disease states. METHO...

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Detalles Bibliográficos
Autores principales: Tseng, Ping-Tao, Lin, Pao-Yen, Lee, Yu, Hung, Chi-Fa, Lung, For-Wey, Chen, Cheng-Sheng, Chong, Mian-Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235206/
https://www.ncbi.nlm.nih.gov/pubmed/25419133
http://dx.doi.org/10.2147/NDT.S71997