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Release of Nonstop Ribosomes Is Essential

Bacterial ribosomes frequently translate to the 3′ end of an mRNA without terminating at a stop codon. Almost all bacteria use the transfer-messenger RNA (tmRNA)-based trans-translation pathway to release these “nonstop” ribosomes and maintain protein synthesis capacity. trans-translation is essenti...

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Detalles Bibliográficos
Autores principales: Feaga, Heather A., Viollier, Patrick H., Keiler, Kenneth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235212/
https://www.ncbi.nlm.nih.gov/pubmed/25389176
http://dx.doi.org/10.1128/mBio.01916-14