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QseC Inhibitors as an Antivirulence Approach for Gram-Negative Pathogens

Invasive pathogens interface with the host and its resident microbiota through interkingdom signaling. The bacterial receptor QseC, which is a membrane-bound histidine sensor kinase, responds to the host stress hormones epinephrine and norepinephrine and the bacterial signal AI-3, integrating interk...

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Detalles Bibliográficos
Autores principales: Curtis, Meredith M., Russell, Regan, Moreira, Cristiano G., Adebesin, Adeniyi M., Wang, Changguang, Williams, Noelle S., Taussig, Ron, Stewart, Don, Zimmern, Philippe, Lu, Biao, Prasad, Ravi N., Zhu, Chen, Rasko, David A., Huntley, Jason F., Falck, John R., Sperandio, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235214/
https://www.ncbi.nlm.nih.gov/pubmed/25389178
http://dx.doi.org/10.1128/mBio.02165-14