Cargando…

Noncanonical G-Protein-Dependent Modulation of Osteoclast Differentiation and Bone Resorption Mediated by Pasteurella multocida Toxin

Pasteurella multocida toxin (PMT) induces atrophic rhinitis in animals, which is characterized by a degradation of nasal turbinate bones, indicating an effect of the toxin on bone cells such as osteoblasts and osteoclasts. The underlying molecular mechanism of PMT was defined as a persistent activat...

Descripción completa

Detalles Bibliográficos
Autores principales: Strack, Julia, Heni, Hannah, Gilsbach, Ralf, Hein, Lutz, Aktories, Klaus, Orth, Joachim H. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235216/
https://www.ncbi.nlm.nih.gov/pubmed/25389180
http://dx.doi.org/10.1128/mBio.02190-14