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Noncanonical G-Protein-Dependent Modulation of Osteoclast Differentiation and Bone Resorption Mediated by Pasteurella multocida Toxin
Pasteurella multocida toxin (PMT) induces atrophic rhinitis in animals, which is characterized by a degradation of nasal turbinate bones, indicating an effect of the toxin on bone cells such as osteoblasts and osteoclasts. The underlying molecular mechanism of PMT was defined as a persistent activat...
Autores principales: | Strack, Julia, Heni, Hannah, Gilsbach, Ralf, Hein, Lutz, Aktories, Klaus, Orth, Joachim H. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235216/ https://www.ncbi.nlm.nih.gov/pubmed/25389180 http://dx.doi.org/10.1128/mBio.02190-14 |
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