Allosteric induction of the CD4-bound conformation of HIV-1 Gp120

BACKGROUND: HIV-1 infection of target cells is mediated via the binding of the viral envelope protein, gp120, to the cell surface receptor CD4. This interaction leads to conformational rearrangements in gp120 forming or revealing CD4 induced (CD4i) epitopes which are critical for the subsequent reco...

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Detalles Bibliográficos
Autores principales: Roitburd-Berman, Anna, Dela, Gal, Kaplan, Gilad, Lewis, George K, Gershoni, Jonathan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235218/
https://www.ncbi.nlm.nih.gov/pubmed/24304511
http://dx.doi.org/10.1186/1742-4690-10-147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235218/
https://www.ncbi.nlm.nih.gov/pubmed/24304511
http://dx.doi.org/10.1186/1742-4690-10-147

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