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Phosphatidylinositol 3-Kinase dependent upregulation of the epidermal growth factor receptor upon Flotillin-1 depletion in breast cancer cells

BACKGROUND: Flotillin-1 and flotillin-2 are two homologous and ubiquitously expressed proteins that are involved in signal transduction and membrane trafficking. Recent studies have reported that flotillins promote breast cancer progression, thus making them interesting targets for breast cancer tre...

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Detalles Bibliográficos
Autores principales: Kurrle, Nina, Ockenga, Wymke, Meister, Melanie, Völlner, Frauke, Kühne, Sina, John, Bincy A, Banning, Antje, Tikkanen, Ritva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235219/
https://www.ncbi.nlm.nih.gov/pubmed/24304721
http://dx.doi.org/10.1186/1471-2407-13-575