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Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer

Cancer cells express an abnormal metabolism characterized by increased glucose consumption owing to genetic mutations and mitochondrial dysfunction. Previous studies indicate that unlike healthy tissues, cancer cells are unable to effectively use ketone bodies for energy. Furthermore, ketones inhibi...

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Detalles Bibliográficos
Autores principales: Poff, AM, Ari, C, Arnold, P, Seyfried, TN, D’Agostino, DP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235292/
https://www.ncbi.nlm.nih.gov/pubmed/24615175
http://dx.doi.org/10.1002/ijc.28809