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Staphylococcus aureus Penicillin-Binding Protein 2 Can Use Depsi-Lipid II Derived from Vancomycin-Resistant Strains for Cell Wall Synthesis

Vancomycin-resistant Staphylococcus aureus (S. aureus) (VRSA) uses depsipeptide-containing modified cell-wall precursors for the biosynthesis of peptidoglycan. Transglycosylase is responsible for the polymerization of the peptidoglycan, and the penicillin-binding protein 2 (PBP2) plays a major role...

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Detalles Bibliográficos
Autores principales: Nakamura, Jun, Yamashiro, Hidenori, Miya, Hiroto, Nishiguchi, Kenzo, Maki, Hideki, Arimoto, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235313/
https://www.ncbi.nlm.nih.gov/pubmed/23873669
http://dx.doi.org/10.1002/chem.201301074