Synthetic Phosphorylation of p38α Recapitulates Protein Kinase Activity

[Image: see text] Through a “tag-and-modify” protein chemical modification strategy, we site-selectively phosphorylated the activation loop of protein kinase p38α. Phosphorylation at natural (180) and unnatural (172) sites created two pure phospho-forms. p38α bearing only a single phosphocysteine (p...

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Detalles Bibliográficos
Autores principales: Chooi, K. Phin, Galan, Sébastien R. G., Raj, Ritu, McCullagh, James, Mohammed, Shabaz, Jones, Lyn H., Davis, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235370/
https://www.ncbi.nlm.nih.gov/pubmed/24393126
http://dx.doi.org/10.1021/ja4095318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235370/
https://www.ncbi.nlm.nih.gov/pubmed/24393126
http://dx.doi.org/10.1021/ja4095318

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