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Synthetic Phosphorylation of p38α Recapitulates Protein Kinase Activity
[Image: see text] Through a “tag-and-modify” protein chemical modification strategy, we site-selectively phosphorylated the activation loop of protein kinase p38α. Phosphorylation at natural (180) and unnatural (172) sites created two pure phospho-forms. p38α bearing only a single phosphocysteine (p...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235370/ https://www.ncbi.nlm.nih.gov/pubmed/24393126 http://dx.doi.org/10.1021/ja4095318 |