A Functional Selectivity Mechanism at the Serotonin-2A GPCR Involves Ligand-Dependent Conformations of Intracellular Loop 2

[Image: see text] With recent progress in determination of G protein-coupled receptor (GPCR) structure with crystallography, a variety of other experimental approaches (e.g., NMR spectroscopy, fluorescent-based assays, mass spectrometry techniques) are also being used to characterize state-specific...

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Detalles Bibliográficos
Autores principales: Perez-Aguilar, Jose Manuel, Shan, Jufang, LeVine, Michael V., Khelashvili, George, Weinstein, Harel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235374/
https://www.ncbi.nlm.nih.gov/pubmed/25314362
http://dx.doi.org/10.1021/ja508394x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235374/
https://www.ncbi.nlm.nih.gov/pubmed/25314362
http://dx.doi.org/10.1021/ja508394x

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