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USING MENDELIAN RANDOMISATION TO INFER CAUSALITY IN DEPRESSION AND ANXIETY RESEARCH

Depression and anxiety co-occur with substance use and abuse at a high rate. Ascertaining whether substance use plays a causal role in depression and anxiety is difficult or impossible with conventional observational epidemiology. Mendelian randomisation uses genetic variants as a proxy for environm...

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Detalles Bibliográficos
Autores principales: Gage, Suzanne H, Smith, George Davey, Zammit, Stanley, Hickman, Matthew, Munafò, Marcus R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235433/
https://www.ncbi.nlm.nih.gov/pubmed/23847157
http://dx.doi.org/10.1002/da.22150