Histone H3.3 and its proteolytically processed form drive a cellular senescence program

The process of cellular senescence generates a repressive chromatin environment, however, the role of histone variants and histone proteolytic cleavage in senescence remains unclear. Using models of oncogene-induced and replicative senescence, here we report novel histone H3 tail cleavage events med...

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Detalles Bibliográficos
Autores principales: Duarte, Luis F., Young, Andrew R. J., Wang, Zichen, Wu, Hsan-Au, Panda, Taniya, Kou, Yan, Kapoor, Avnish, Hasson, Dan, Mills, Nicholas R., Ma’ayan, Avi, Narita, Masashi, Bernstein, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235654/
https://www.ncbi.nlm.nih.gov/pubmed/25394905
http://dx.doi.org/10.1038/ncomms6210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235654/
https://www.ncbi.nlm.nih.gov/pubmed/25394905
http://dx.doi.org/10.1038/ncomms6210

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