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Histone H3.3 and its proteolytically processed form drive a cellular senescence program
The process of cellular senescence generates a repressive chromatin environment, however, the role of histone variants and histone proteolytic cleavage in senescence remains unclear. Using models of oncogene-induced and replicative senescence, here we report novel histone H3 tail cleavage events med...
Autores principales: | Duarte, Luis F., Young, Andrew R. J., Wang, Zichen, Wu, Hsan-Au, Panda, Taniya, Kou, Yan, Kapoor, Avnish, Hasson, Dan, Mills, Nicholas R., Ma’ayan, Avi, Narita, Masashi, Bernstein, Emily |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235654/ https://www.ncbi.nlm.nih.gov/pubmed/25394905 http://dx.doi.org/10.1038/ncomms6210 |
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