Similarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a “Bookmarking” Oncoprotein that Alters the Host Cell Epigenotype?

EBNA1, a nuclear protein expressed in all EBV-associated neoplasms is indispensable for the maintenance of the viral episomes in latently infected cells. EBNA1 may induce genetic alterations by upregulating cellular recombinases, production of reactive oxygen species (ROS) and affecting p53 levels a...

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Detalles Bibliográficos
Autores principales: Niller, Hans Helmut, Minarovits, Janos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235684/
https://www.ncbi.nlm.nih.gov/pubmed/25436603
http://dx.doi.org/10.3390/pathogens1010037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235684/
https://www.ncbi.nlm.nih.gov/pubmed/25436603
http://dx.doi.org/10.3390/pathogens1010037

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