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Curcumin Reduces Amyloid Fibrillation of Prion Protein and Decreases Reactive Oxidative Stress

Misfolding and aggregation into amyloids of the prion protein (PrP) is responsible for the development of fatal transmissible neurodegenerative diseases. Various studies on curcumin demonstrate promise for the prevention of Alzheimer’s disease and inhibition of PrP(res) accumulation. To evaluate the...

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Detalles Bibliográficos
Autores principales: Lin, Chi-Fen, Yu, Kun-Hua, Jheng, Cheng-Ping, Chung, Raymond, Lee, Cheng-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235698/
https://www.ncbi.nlm.nih.gov/pubmed/25437204
http://dx.doi.org/10.3390/pathogens2030506