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Maternal Inflammation Contributes to Brain Overgrowth and Autism-Associated Behaviors through Altered Redox Signaling in Stem and Progenitor Cells

A period of mild brain overgrowth with an unknown etiology has been identified as one of the most common phenotypes in autism. Here, we test the hypothesis that maternal inflammation during critical periods of embryonic development can cause brain overgrowth and autism-associated behaviors as a resu...

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Detalles Bibliográficos
Autores principales: Le Belle, Janel E., Sperry, Jantzen, Ngo, Amy, Ghochani, Yasmin, Laks, Dan R., López-Aranda, Manuel, Silva, Alcino J., Kornblum, Harley I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235743/
https://www.ncbi.nlm.nih.gov/pubmed/25418720
http://dx.doi.org/10.1016/j.stemcr.2014.09.004