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Endogenous lung surfactant inspired pH responsive nanovesicle aerosols: Pulmonary compatible and site-specific drug delivery in lung metastases

Concerns related to pulmonary toxicity and non-specificity of nanoparticles have limited their clinical applications for aerosol delivery of chemotherapeutics in lung cancer. We hypothesized that pulmonary surfactant mimetic nanoparticles that offer pH responsive release specifically in tumor may be...

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Detalles Bibliográficos
Autores principales: Joshi, Nitin, Shirsath, Nitesh, Singh, Ankur, Joshi, Kalpana S., Banerjee, Rinti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235800/
https://www.ncbi.nlm.nih.gov/pubmed/25403950
http://dx.doi.org/10.1038/srep07085