Cargando…
Modulation of the Maladaptive Stress Response to Manage Diseases of Protein Folding
Diseases of protein folding arise because of the inability of an altered peptide sequence to properly engage protein homeostasis components that direct protein folding and function. To identify global principles of misfolding disease pathology we examined the impact of the local folding environment...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236052/ https://www.ncbi.nlm.nih.gov/pubmed/25406061 http://dx.doi.org/10.1371/journal.pbio.1001998 |