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Late-Onset of Spinal Neurodegeneration in Knock-In Mice Expressing a Mutant BiP
Most human neurodegenerative diseases are sporadic, and appear later in life. While the underlying mechanisms of the progression of those diseases are still unclear, investigations into the familial forms of comparable diseases suggest that endoplasmic reticulum (ER) stress is involved in the pathog...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236098/ https://www.ncbi.nlm.nih.gov/pubmed/25405877 http://dx.doi.org/10.1371/journal.pone.0112837 |