Lymphotoxin-LIGHT Pathway Regulates the Interferon Signature in Rheumatoid Arthritis

A subset of patients with autoimmune diseases including rheumatoid arthritis (RA) and lupus appear to be exposed continually to interferon (IFN) as evidenced by elevated expression of IFN induced genes in blood cells. In lupus, detection of endogenous chromatin complexes by the innate sensing machin...

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Detalles Bibliográficos
Autores principales: Bienkowska, Jadwiga, Allaire, Norm, Thai, Alice, Goyal, Jaya, Plavina, Tatiana, Nirula, Ajay, Weaver, Megan, Newman, Charlotte, Petri, Michelle, Beckman, Evan, Browning, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236099/
https://www.ncbi.nlm.nih.gov/pubmed/25405351
http://dx.doi.org/10.1371/journal.pone.0112545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236099/
https://www.ncbi.nlm.nih.gov/pubmed/25405351
http://dx.doi.org/10.1371/journal.pone.0112545

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