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Lymphotoxin-LIGHT Pathway Regulates the Interferon Signature in Rheumatoid Arthritis
A subset of patients with autoimmune diseases including rheumatoid arthritis (RA) and lupus appear to be exposed continually to interferon (IFN) as evidenced by elevated expression of IFN induced genes in blood cells. In lupus, detection of endogenous chromatin complexes by the innate sensing machin...
Autores principales: | Bienkowska, Jadwiga, Allaire, Norm, Thai, Alice, Goyal, Jaya, Plavina, Tatiana, Nirula, Ajay, Weaver, Megan, Newman, Charlotte, Petri, Michelle, Beckman, Evan, Browning, Jeffrey L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236099/ https://www.ncbi.nlm.nih.gov/pubmed/25405351 http://dx.doi.org/10.1371/journal.pone.0112545 |
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