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On the Normalization of the Minimum Free Energy of RNAs by Sequence Length

The minimum free energy (MFE) of ribonucleic acids (RNAs) increases at an apparent linear rate with sequence length. Simple indices, obtained by dividing the MFE by the number of nucleotides, have been used for a direct comparison of the folding stability of RNAs of various sizes. Although this norm...

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Detalles Bibliográficos
Autor principal: Trotta, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236180/
https://www.ncbi.nlm.nih.gov/pubmed/25405875
http://dx.doi.org/10.1371/journal.pone.0113380