Existence of Molten Globule State in Homocysteine-Induced Protein Covalent Modifications

Homocysteine thiolactone is a toxic metabolite produced from homocysteine by amino-acyl t-RNA synthetase in error editing reaction. The basic cause of toxicity of homocysteine thiolactone is believed to be due to the adduct formation with lysine residues (known as protein N-homocysteinylation) leadi...

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Detalles Bibliográficos
Autores principales: Kumar, Tarun, Sharma, Gurumayum Suraj, Singh, Laishram Rajendrakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236184/
https://www.ncbi.nlm.nih.gov/pubmed/25405350
http://dx.doi.org/10.1371/journal.pone.0113566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236184/
https://www.ncbi.nlm.nih.gov/pubmed/25405350
http://dx.doi.org/10.1371/journal.pone.0113566

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