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Characterization of Albendazole-Randomly Methylated-β-Cyclodextrin Inclusion Complex and In Vivo Evaluation of Its Antihelmitic Activity in a Murine Model of Trichinellosis

Albendazole is a benzimidazole carbamate extensively used in oral chemotherapy against intestinal parasites, due to its broad spectrum activity, good tolerance and low cost. However, the drug has the disadvantage of poor bioavailability due to its very low solubility in water; as a consequence, a ve...

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Detalles Bibliográficos
Autores principales: García, Agustina, Leonardi, Darío, Vasconi, María D., Hinrichsen, Lucila I., Lamas, María C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236198/
https://www.ncbi.nlm.nih.gov/pubmed/25406084
http://dx.doi.org/10.1371/journal.pone.0113296