Cargando…
Characterization of Albendazole-Randomly Methylated-β-Cyclodextrin Inclusion Complex and In Vivo Evaluation of Its Antihelmitic Activity in a Murine Model of Trichinellosis
Albendazole is a benzimidazole carbamate extensively used in oral chemotherapy against intestinal parasites, due to its broad spectrum activity, good tolerance and low cost. However, the drug has the disadvantage of poor bioavailability due to its very low solubility in water; as a consequence, a ve...
Autores principales: | García, Agustina, Leonardi, Darío, Vasconi, María D., Hinrichsen, Lucila I., Lamas, María C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236198/ https://www.ncbi.nlm.nih.gov/pubmed/25406084 http://dx.doi.org/10.1371/journal.pone.0113296 |
Ejemplares similares
-
Modified β-Cyclodextrin Inclusion Complex to Improve the Physicochemical Properties of Albendazole. Complete In Vitro Evaluation and Characterization
por: García, Agustina, et al.
Publicado: (2014) -
The Use of Cyclodextrin Inclusion Complexes to Increase the Solubility and Pharmacokinetic Profile of Albendazole
por: Ding, Yili, et al.
Publicado: (2023) -
Trichinellosis Outbreak
por: Marva, Esther, et al.
Publicado: (2005) -
Trichinellosis : proceedings of the Ninth International Conference on Trichinellosis, August 19-22, 1996, Mexico City /
Publicado: (1996) -
Super Aqueous Solubility of Albendazole in β-Cyclodextrin for Parenteral Application in Cancer therapy
por: Pillai, Krishna, et al.
Publicado: (2017)