Enhanced AMPA receptor function promotes cerebellar long-term depression rather than potentiation

Ampakines are allosteric modulators of AMPA receptors that facilitate hippocampal long-term potentiation (LTP) and learning, and have been considered for the treatment of cognition and memory deficits. Here, we show that the ampakine CX546 raises the amplitude and slows the decay time of excitatory...

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Detalles Bibliográficos
Autores principales: van Beugen, Boeke J., Qiao, Xin, Simmons, Dana H., De Zeeuw, Chris I., Hansel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236409/
https://www.ncbi.nlm.nih.gov/pubmed/25403454
http://dx.doi.org/10.1101/lm.035220.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236409/
https://www.ncbi.nlm.nih.gov/pubmed/25403454
http://dx.doi.org/10.1101/lm.035220.114

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