Nck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression

BACKGROUND: Activation of the PI3K/Akt pathway mediates crucial cellular functions regulated by receptor tyrosine kinases, such as cell growth, proliferation, survival and metabolism. Previously, we reported that the whole-body knockout of the Src homology domain-containing adaptor protein Nck1 impr...

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Detalles Bibliográficos
Autores principales: Li, Hui, Dusseault, Julie, Larose, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236421/
https://www.ncbi.nlm.nih.gov/pubmed/25398386
http://dx.doi.org/10.1186/s12964-014-0071-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236421/
https://www.ncbi.nlm.nih.gov/pubmed/25398386
http://dx.doi.org/10.1186/s12964-014-0071-9

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