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Limited role of regulatory T cells during acute Theiler virus-induced encephalitis in resistant C57BL/6 mice
BACKGROUND: Theiler’s murine encephalomyelitis virus (TMEV) infection represents a commonly used infectious animal model to study various aspects of the pathogenesis of multiple sclerosis (MS). In susceptible SJL mice, dominant activity of Foxp3(+) CD4(+) regulatory T cells (Tregs) in the CNS partly...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236492/ https://www.ncbi.nlm.nih.gov/pubmed/25391297 http://dx.doi.org/10.1186/s12974-014-0180-9 |