Dual effects of a targeted small-molecule inhibitor (cabozantinib) on immune-mediated killing of tumor cells and immune tumor microenvironment permissiveness when combined with a cancer vaccine

BACKGROUND: Growing awareness of the complexity of carcinogenesis has made multimodal therapies for cancer increasingly compelling and relevant. In recent years, immunotherapy has gained acceptance as an active therapeutic approach to cancer treatment, even though cancer is widely considered an immu...

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Detalles Bibliográficos
Autores principales: Kwilas, Anna R, Ardiani, Andressa, Donahue, Renee N, Aftab, Dana T, Hodge, James W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236498/
https://www.ncbi.nlm.nih.gov/pubmed/25388653
http://dx.doi.org/10.1186/s12967-014-0294-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236498/
https://www.ncbi.nlm.nih.gov/pubmed/25388653
http://dx.doi.org/10.1186/s12967-014-0294-y

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