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Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse

BACKGROUND: Acetaminophen (APAP) is one of the most widely used analgesic and antipyretic pharmaceutical substances in the world and accounts for most cases of drug induced liver injury resulting in acute liver failure. Acute liver failure initiates a sterile inflammatory response with release of cy...

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Detalles Bibliográficos
Autores principales: Steinebrunner, Niels, Mogler, Carolin, Vittas, Spiros, Hoyler, Birgit, Sandig, Catharina, Stremmel, Wolfgang, Eisenbach, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236504/
https://www.ncbi.nlm.nih.gov/pubmed/25139304
http://dx.doi.org/10.1186/1471-230X-14-148