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Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse
BACKGROUND: Acetaminophen (APAP) is one of the most widely used analgesic and antipyretic pharmaceutical substances in the world and accounts for most cases of drug induced liver injury resulting in acute liver failure. Acute liver failure initiates a sterile inflammatory response with release of cy...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236504/ https://www.ncbi.nlm.nih.gov/pubmed/25139304 http://dx.doi.org/10.1186/1471-230X-14-148 |