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Impact of pre-imputation SNP-filtering on genotype imputation results

BACKGROUND: Imputation of partially missing or unobserved genotypes is an indispensable tool for SNP data analyses. However, research and understanding of the impact of initial SNP-data quality control on imputation results is still limited. In this paper, we aim to evaluate the effect of different...

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Detalles Bibliográficos
Autores principales: Roshyara, Nab Raj, Kirsten, Holger, Horn, Katrin, Ahnert, Peter, Scholz, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236550/
https://www.ncbi.nlm.nih.gov/pubmed/25112433
http://dx.doi.org/10.1186/s12863-014-0088-5