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Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria

BACKGROUND: The hapalindole-type family of natural products is a group of hybrid isoprenoid-indole alkaloids, produced solely by members of the Subsection V cyanobacterial strains. This family broadly includes the hapalindoles, welwitindolinones, fisherindoles and ambiguines amongst others, all of w...

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Detalles Bibliográficos
Autores principales: Micallef, Melinda L, Sharma, Deepti, Bunn, Brittney M, Gerwick, Lena, Viswanathan, Rajesh, Moffitt, Michelle C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236562/
https://www.ncbi.nlm.nih.gov/pubmed/25198896
http://dx.doi.org/10.1186/s12866-014-0213-7